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Vaccines in the short-term may accelerate the transition from subclinical MS to overt autoimmunity in patients with existing disease

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Vaccines and the Risk of Multiple Sclerosis and Other Central Nervous System Demyelinating Diseases JAMA Neurol. Published online October 20, 2014. doi:10.1001/jamaneurol.2014.2633 Importance  Because vaccinations are common, even a small increased risk of multiple sclerosis (MS) or other acquired central nervous system demyelinating syndromes (CNS ADS) could have a significant effect on public health. Objective  To determine whether vaccines, particularly those for hepatitis B (HepB) and human papillomavirus (HPV), increase the risk of MS or other CNS ADS. Design, Setting, and Participants  A nested case-control study was conducted using data obtained from the complete electronic More…

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